Search on: RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE 
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Descriptor English:   Ribonucleoside Diphosphate Reductase 
Descriptor Spanish:   Ribonucleósido Difosfato Reductasa 
Descriptor Portuguese:   Ribonucleosídeo Difosfato Redutase 
Synonyms English:   Diphosphate Reductase, Ribonucleoside
Reductase, Ribonucleoside Diphosphate
Reductase, UDP
UDP Reductase  
Tree Number:   D08.811.682.810.567
Definition English:   An enzyme of the oxidoreductase class that catalyzes the formation of 2'-deoxyribonucleotides from the corresponding ribonucleotides using NADPH as the ultimate electron donor. The deoxyribonucleoside diphosphates are used in DNA synthesis. (From Dorland, 27th ed) EC 1.17.4.1. 
History Note English:   91(75); was see under RIBONUCLEOTIDE REDUCTASES 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   12671 
Unique Identifier:   D012262 

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